(images from Neuroskeptic)
Neuroskeptic reports on some disturbing news that the results of fMRI studies can be seriously impacted by the software package used to analyze the results. There are several packages available and while most do much the same thing, at least one uses a unique statistical approach which produces different results. Not "better" or "worse" mind you, just different. The image above contrasts results using the same data but different analysis software. Money quote:
Analysis using both programs revealed that during the processing of emotional faces, as compared to the baseline stimulus, there was an increased activation in the visual areas (occipital, fusiform and lingual gyri), in the cerebellum, in the parietal cortex [etc] ... Conversely, the temporal regions, insula and putamen were found to be activated using the XBAM analysis software only (emphasis added).
The comments on Neuroskeptic's post are detailed and instructive.